Vascular Perfusion Abnormalities in Infants with Spinal Muscular Atrophy

被引：94

作者：

de Queiroz Campos Araujo, Alexandra Prufer ^{[1
]}

Araujo, Mario ^{[2
]}

Swoboda, Kathryn J. ^{[3
]}

机构：

[1] Univ Fed Rio de Janeiro, BR-21941912 Rio De Janeiro, Brazil

[2] Univ Estado Rio De Janeiro, Rio De Janeiro, Brazil

[3] Univ Utah, Sch Med, Pediat Motor Disorders Res Program, Salt Lake City, UT USA

来源：

JOURNAL OF PEDIATRICS | 2009年 / 155卷 / 02期

关键词：

AMYOTROPHIC-LATERAL-SCLEROSIS; SYMPATHETIC SKIN-RESPONSE; DISEASE; TYPE-1; MUSCLE;

D O I：

10.1016/j.jpeds.2009.01.071

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

Spinal muscular atrophy (SMA) is an important cause of death in children and SMA type 1, also known as Werdnig-Hoffman disease, is the most severe form of this disease. We report 2 cases of infants with SMA I in whom a distal necrosis developed, a feature not previously reported. Poor perfusion, autonomic dysfunction, and position-dependent factors may all play a role in the development of this complication. (J Pediatr 2009,155:292-4)

引用

页码：292 / 294

页数：3

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