Solid-phase synthesis of 5-biphenyl-2-yl-1H-tetrazoles

被引：27

作者：

Kivrakidou, O

Bräse, S

Hulshorst, F

Griebenow, N

机构：

[1] Bayer AG, Pharma Res Ctr, Bayer Hlth Care, D-42096 Wuppertal, Germany

[2] Univ Karlsruhe, Inst Inorgan Chem, D-76131 Karlsruhe, Germany

[3] Sugaris GmbH, D-48161 Munster, Germany

来源：

ORGANIC LETTERS | 2004年 / 6卷 / 07期

关键词：

D O I：

10.1021/ol0498848

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The combinatorial synthesis of novel biphenyl tetrazoles is described. Key steps include the simultaneous biphenyl formation and phenol deallylation under Suzuki cross-coupling conditions as well as the tetrazole ring formation on solid support. A representative library of 20 biphenyl tetrazoles was synthesized.

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页码：1143 / 1146

页数：4

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