Association of aortic stenosis with platelet hyperaggregability and impaired responsiveness to nitric oxide

被引：39

作者：

Chirkov, YY ^{[1
]}

Holmes, AS ^{[1
]}

Willoughby, SR ^{[1
]}

Stewart, S ^{[1
]}

Horowitz, JD ^{[1
]}

机构：

[1] Univ Adelaide, Queen Elizabeth Hosp, Dept Med, Cardiol Unit, Adelaide, SA, Australia

来源：

AMERICAN JOURNAL OF CARDIOLOGY | 2002年 / 90卷 / 05期

关键词：

D O I：

10.1016/S0002-9149(02)02536-5

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Aortic stenosis, irrespective of the presence or absence of coronary artery disease, is associated with platelet hyperaggregability and hyporesponsiveness to antiaggregatory effects of the nitric oxide donor sodium nitroprusside. Treatment with the prophylactic antianginal agent perhexilene improves platelet responsiveness to nitric oxide.

引用

页码：551 / +

页数：5

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