Fungal melanin inhibitor and related compounds from Penicillium decumbens

被引：59

作者：

Fujii, Y ^{[1
]}

Asahara, M

Ichinoe, M

Nakajima, H

机构：

[1] Yonago Natl Coll Technol, Dept Mat Sci, Yonago, Tottori 6838502, Japan

[2] Tottori Univ, Fac Engn, Dept Mat Sci, Tottori 6808552, Japan

[3] Tokyo Kasei Univ, Food Microbiol Lab, Tokyo 1730003, Japan

[4] Tottori Univ, Fac Agr, Dept Agr Chem, Tottori 6808553, Japan

来源：

PHYTOCHEMISTRY | 2002年 / 60卷 / 07期

关键词：

Penicillium decumbens; melanin; inhibitor; Magnaporthe grisea; fungal metabolite; decumbenone; polyketide;

D O I：

10.1016/S0031-9422(02)00196-6

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 [生物化学与分子生物学]; 081704 [应用化学];

摘要：

Two polyketides, decumbenones A and B, and versiol were isolated from the culture filtrate of the fungus, Penicillium decumbens. Their respective structures were 1-(2.8-dihydroxy-1,2,6-trimethyl-1,2,6,7.8,8a-hexahydronaphthalen-1-yl)-3-hydroxy-1-propanone and 1-(2,8-dihydroxy-1,2,6-trimethyl-1,2,4a.5,6,7,8,8a-octahydronaphthalen-1-yl)-3-hydroxy-1-propanone based on NMR spectroscopic data, chemical conversion, and X-ray analysis. Decumbenone A inhibited melanization in Magnaporthe grisea, the rice blast pathogen, whereas decumbenone B like versiol did not. (C) 2002 Elsevier Science Ltd. All rights reserved.

引用

页码：703 / 708

页数：6

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