Implementation of European standards of care for cystic fibrosis - Control and treatment of infection

被引:30
作者
Elborn, J. S. [1 ]
Hodson, M. [2 ]
Bertram, C. [3 ]
机构
[1] Queens Univ Belfast, Belfast City Hosp, Resp Med Res Grp, Belfast BT9 7AB, Antrim, North Ireland
[2] Royal Brompton Hosp, Dept Cyst Fibrosis, London SW3 6NP, England
[3] Independent Consultant, London, England
关键词
Cystic fibrosis; Infection; Pseudomonas aeruginosa; Survey; European; PSEUDOMONAS-AERUGINOSA INFECTION; LUNG INFECTION; COLONIZATION; COLISTIN; CHILDREN; EXACERBATIONS; EPIDEMIOLOGY; TOBRAMYCIN; CONSENSUS; THERAPY;
D O I
10.1016/j.jcf.2009.03.001
中图分类号
R56 [呼吸系及胸部疾病];
学科分类号
摘要
Background: Several guidelines oil infection control and treatment of infection exist for cystic fibrosis (CF) caregivers, although the extent of implementation is variable. Methods: Adherence to European Consensus Guidelines for CF was Studied by sending surveys to named healthcare professionals in 487 European CF centres/units. Qualitative data analysis was performed. Results: A total of 177/547 (32%) Surveys were returned. Infection control policies were implemented by most (77%) respondents. Separation of patients with Burkholderia cepacia was more common in adults (95%) than children (9%), and was implemented by 53% of respondents for Pseudomonas aeruginosa. Nebulised colistin Plus oral ciprofloxacin was the most common (43%) therapy for P. aeruginosa infection. First infections of P aeruginosa were usually treated with inhaled tobramycin; 41% of repondents did not intervene until lung function deteriorated. Most exacerbations were treated for less than the recommended period. Conclusions: European Consensus Guidelines are widely adhered to. Areas for improvement, include: initiating therapy for exacerbations early, separating infected patients and optimising duration of antibiotic therapy. (C) 2009 Published by Elsevier B.V. on behalf of European Cystic Fibrosis Society.
引用
收藏
页码:211 / 217
页数:7
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