The placebo effect in neurological disorders

被引：125

作者：

de la Fuente-Fernández, R ^{[1
]}

Schulzer, M ^{[1
]}

Stoessel, AJ ^{[1
]}

机构：

[1] Univ British Columbia, Pacific Parkinsons Res Ctr, Vancouver, BC V6T 2B5, Canada

来源：

LANCET NEUROLOGY | 2002年 / 1卷 / 02期

基金：

加拿大健康研究院;

关键词：

D O I：

10.1016/S1474-4422(02)00038-8

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Recent evidence suggests that the placebo effect is mediated by the dopaminergic reward mechanisms in the human brain and that it is related to the expectation of clinical benefit. On the basis of this theory, we propose some criteria for the proper investigation of the placebo effect, and review the evidence for a placebo effect in Parkinson's disease, depression, pain, and other neurological disorders. We also discuss the evidence for the use of placebos in long-term substitution programmes for the treatment of drug addiction.

引用

页码：85 / 91

页数：7

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