Amphiphilic TiO2 Nanotube Arrays: An Actively Controllable Drug Delivery System

被引:374
作者
Song, Yan-Yan [1 ]
Schmidt-Stein, Felix [1 ]
Bauer, Sebastian [1 ]
Schmuki, Patrik [1 ]
机构
[1] Univ Erlangen Nurnberg, Dept Mat Sci, D-91058 Erlangen, Germany
关键词
LAYERS; NANOPARTICLES; SURFACES; MICROCARRIERS; TITANIUM; RELEASE; GROWTH; AG;
D O I
10.1021/ja810130h
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Amphiphilic TiO2 nanotube arrays are faribricated by a two-step anodization procedure combined with hydrophobic monolayer modification after the first step. These tubes can be used as biomotecular carriers, where the outer hydrophobic barrier provides an efficient cap against drug leaching to the environment. By utitizing the photocatalytic ability of TiO2 a precisely controlled removal of the cap and a highly controlled release of the hydrophilic payload (drug) can be achieved.
引用
收藏
页码:4230 / +
页数:4
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