Antimicrobial peptides in the interactions between insects and flagellate parasites

被引：80

作者：

Boulanger, Nathalie ^{[1
]}

Bulet, Philippe

Lowenberger, Carl

机构：

[1] Univ Louis Pasteur Strasbourg 1, Fac Pharm, Equipe Accueil 3432, F-67401 Illkirch Graffenstaden, France

[2] Atheris Labs, CH-1233 Bernex, Switzerland

[3] Simon Fraser Univ, Dept Biol Sci, Canada Res Chair, Burnaby, BC V5A 1S6, Canada

来源：

TRENDS IN PARASITOLOGY | 2006年 / 22卷 / 06期

基金：

加拿大自然科学与工程研究理事会;

关键词：

D O I：

10.1016/j.pt.2006.04.003

中图分类号：

R38 [医学寄生虫学]; Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ; 100103 ;

摘要：

Innate immunity has a key role in the control of microbial infections in both vertebrates and invertebrates. In insects, including vectors that transmit parasites that cause major human and animal diseases, antimicrobial peptides (AMPs) are important components of innate immunity. AMPs are induced upon parasitic infections and can participate in regulating parasite development in the digestive tract and in the hemolymph. This review presents our current knowledge of a field that is in its infancy: the role of innate immunity in different models of insects infected with flagellate parasites, and in particular the potential role of AMPs in regulating these parasitic infections.

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收藏

页码：262 / 268

页数：7

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