A fusidic acid-resistant epidemic strain of Staphylococcus aureus carries the fusB determinant, whereas fusA mutations are prevalent in other resistant isolates

被引：72

作者：

O'Neill, AJ

Larsen, AR

Henriksen, AS

Chopra, I ^{[1
]}

机构：

[1] Univ Leeds, Antimicrobial Res Ctr, Leeds LS2 9JT, W Yorkshire, England

[2] Univ Leeds, Sch Biochem & Microbiol, Leeds LS2 9JT, W Yorkshire, England

[3] State Serum Inst, Dept Res & Dev, Copenhagen, Denmark

[4] Leo Pharma, Ballerup, Denmark

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2004年 / 48卷 / 09期

关键词：

D O I：

10.1128/AAC.48.9.3594-3597.2004

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Fusidic acid-resistant epidemic Staphylococcus aureus strains causing impetigo bullosa have been reported in Scandinavia. We show that these strains form part of a European epidemic clonotype that carries the fusB determinant. In contrast, resistance to fusidic acid in a collection of nonepidemic strains resulted primarily from mutations in fusA.

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页码：3594 / 3597

页数：4

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