Immune (dys)regulation in multiple sclerosis: role of the CD95-CD95 ligand system

被引：68

作者：

Zipp, F ^{[1
]}

Krammer, PH

Weller, M

机构：

[1] Charite, Dept Neurol, D-10098 Berlin, Germany

[2] German Canc Res Ctr, D-69129 Heidelberg, Germany

[3] Univ Tubingen, Dept Neurol, D-72076 Tubingen, Germany

来源：

IMMUNOLOGY TODAY | 1999年 / 20卷 / 12期

关键词：

D O I：

10.1016/S0167-5699(99)01545-5

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

T cells specific for myelin antigens are thought to initiate and perpetuate the immune process behind multiple sclerosis. Apoptosis is a key regulatory mechanism that determines T-cell fate and might mediate tissue damage. Here, Frauke Zipp, Peter Krammer and Michael Weller discuss the role of the CD95-CD95 ligand system in multiple sclerosis.

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页码：550 / 554

页数：5

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