High Concentrations of Manganese in Mueller-Hinton Agar Increase MICs of Tigecycline Determined by Etest

被引:59
作者
Fernandez-Mazarrasa, Carlos [1 ]
Mazarrasa, Olav [3 ]
Calvo, Jorge [1 ]
del Arco, Asuncion [1 ]
Martinez-Martinez, Luis [1 ,2 ]
机构
[1] Univ Hosp Marques Valdecilla, Microbiol Serv, Santander 39008, Spain
[2] Univ Cantabria, Dept Mol Biol, Sch Med, E-39005 Santander, Spain
[3] Occupat Safety & Hlth Ctr, Santander, Spain
关键词
REDUCING REAGENT OXYRASE; PSEUDOMONAS-AERUGINOSA; MULTIPLEX PCR; SUSCEPTIBILITY; GENTAMICIN; MAGNESIUM; COPPER; ZINC;
D O I
10.1128/JCM.02464-08
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
MICs of tigecycline determined by Etest were 4 to 12 times (three ATCC strains) and 2 to 8 times (50 clinical isolates) higher in Mueller-Hinton agar from Merck than in Mueller-Hinton agar from either Oxoid or Difco. This was related to a much higher concentration of manganese in the medium from Merck.
引用
收藏
页码:827 / 829
页数:3
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