Fatal cardiovascular collapse during ethanol sclerotherapy of a venous malformation

被引:29
作者
Chapot, R [1 ]
Laurent, A
Enjolras, O
Payen, D
Houdart, E
机构
[1] Hop Univ Lariboisiere, Serv Neuroradiol & Angiog Therpeut, F-75475 Paris, France
[2] Hop Univ Lariboisiere, Dept Anesthesie Reanimat, F-75475 Paris, France
[3] Hop Univ Lariboisiere, Inst Rech Circulat, F-75475 Paris, France
来源
INTERVENTIONAL NEURORADIOLOGY | 2002年 / 8卷 / 03期
关键词
complication; alcohol; sclerotherapy; venous malformation;
D O I
10.1177/159101990200800314
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
We report a case of fatal cardiovascular collapse that occurred during Ethanol sclerotherapy of a venous malformation in a 21-year-old woman. The malformation was located on the anterior part of the thigh. Fifty ml of a mixture of Ethanol, Ethibloc and Lipiodol containing 35 ml of Ethanol (0.52 ml/kg) were injected under fluoroscopy. A major drop in arterial pressure was recorded after release of the tourniquet placed at the thigh root. The patient died after four hours of intensive cardiac reanimation. Her blood alcohol level was 0.4 g/l one hour after the end of the intervention. The cardiac toxicity of ethanol depends more on the potential acute venous contamination than on the blood alcohol concentration. The currently admitted "safety limit" of 1 ml/kg of bodyweight for ethanol sclerotherapy of venous malformations is certainly unsafe and must be redefined.
引用
收藏
页码:321 / 324
页数:4
相关论文
共 7 条
[1]   FATAL OUTCOME AFTER ETHANOL RENAL ABLATION IN CHILD WITH END-STAGE KIDNEYS [J].
GAREL, L ;
MARESCHAL, JL ;
GAGNADOUX, MF ;
PARIENTE, D ;
GUILBERT, M ;
SAUVEGRAIN, J .
AMERICAN JOURNAL OF ROENTGENOLOGY, 1986, 146 (03) :593-594
[2]  
Gelczer RK, 1998, J ULTRAS MED, V17, P531
[3]  
Lasjaunias P, 1987, SURG NEUROANGIOGRAPH, V2, P40
[4]   Serum ethanol levels in children and adults after ethanol embolization or sclerotherapy for vascular anomalies [J].
Mason, KP ;
Michna, E ;
Zurakowski, D ;
Koka, BV ;
Burrows, PE .
RADIOLOGY, 2000, 217 (01) :127-132
[5]   Venous malformations: Sclerotherapy with a mixture of ethanol and lipiodol [J].
Suh, JS ;
Shin, KH ;
Na, JB ;
Won, JY ;
Hahn, SB .
CARDIOVASCULAR AND INTERVENTIONAL RADIOLOGY, 1997, 20 (04) :268-273
[6]   SYMPTOMATIC VASCULAR MALFORMATIONS - ETHANOL EMBOLOTHERAPY [J].
YAKES, WF ;
HAAS, DK ;
PARKER, SH ;
GIBSON, MD ;
HOPPER, KD ;
MULLIGAN, JS ;
PEVSNER, PH ;
JOHNS, JC ;
CARTER, TE .
RADIOLOGY, 1989, 170 (03) :1059-1066
[7]  
YAKES WF, 1999, INTERV NEURORADIOL, P327