Globulixanthones A and B, two new cytotoxic xanthones with isoprenoid groups from the root bark of Symphonia globulifera

被引：31

作者：

Nkengfack, AE

Mkounga, P

Fomum, ZT

Meyer, M

Bodo, B

机构：

[1] Univ Yaounde 1, Fac Sci, Dept Organ Chem, Yaounde, Cameroon

[2] Natl Museum Nat Hist, URA 401, Lab Chim Substances Nat, F-75005 Paris 05, France

来源：

JOURNAL OF NATURAL PRODUCTS | 2002年 / 65卷 / 05期

关键词：

D O I：

10.1021/np010478w

中图分类号：

Q94 [植物学];

学科分类号：

071001 [植物学];

摘要：

Bioassay-guided fractionation of a root bark extract of Symphonia globulifera has yielded, in addition to stigmasterol, two new xanthones with isoprenoid units, named globulixanthones A (1) and B (2). The structures of these compounds have been elucidated by spectroscopic means. They possess significant cytotoxicity in vitro against the KB cell line.

引用

页码：734 / 736

页数：3

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