Additional cytotoxic diacetylenes from the stony coral Montipora sp.

被引：10

作者：

Alam, N

Hong, JK

Lee, CO

Choi, JS

Im, KS

Jung, JH ^{[1
]}

机构：

[1] Pusan Natl Univ, Coll Pharm, Pusan 609735, South Korea

[2] Korea Basic Sci Inst, Seoul, South Korea

[3] Korea Res Inst Chem Technol, Taejon 305606, South Korea

[4] Pukyung Natl Univ, Pusan, South Korea

来源：

CHEMICAL & PHARMACEUTICAL BULLETIN | 2002年 / 50卷 / 05期

关键词：

stony coral; Montipora sp; diacetylene; cytotoxicity;

D O I：

10.1248/cpb.50.661

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Three new diacetylenes (1, 4, 6) have been isolated as cytotoxic constituents from the methanolic extract of the stony coral Montipora sp. The structures have been elucidated on the basis of spectroscopic evidence. The compounds were evaluated for cytotoxicity against a small panel of human tumor cell lines and showed moderate to significant activity.

引用

页码：661 / 662

页数：2

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