Pharmacological treatment of chronic heart failure

被引：24

作者：

Adorisio, Rachele

De Luca, Leonardo

Rossi, Joseph

Gheorghiade, Mihai

机构：

[1] Northwestern Univ, Feinberg Sch Med, Chicago, IL 60611 USA

[2] Bambino Gesu Pediat Hosp, Dept Cardiol & Cardiac Surg, Rome, Italy

[3] European Hosp, Div Cardiol, Rome, Italy

来源：

HEART FAILURE REVIEWS | 2006年 / 11卷 / 02期

关键词：

heart failure; drugs; angiotensin-converting enzyme inhibitors; beta-blockers; diuretics; digitalis;

D O I：

10.1007/s10741-006-9482-z

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Heart failure (HF) is associated with a high morbidity and mortality in the Western World. Our knowledge of the epidemiology, pathophysiology, and therapy has improved dramatically during the last 20 years. Pharmacological treatment, as it stands today, is a combination of preventive and symptomatic strategies. The mainstay life-saving drugs are angiotensin-converting enzyme inhibitors and beta-blockers. Additional benefits are obtained when angiotensin-receptor blockers or aldosterone antagonists are added. Digitalis and/or diuretics are useful for symptom reduction. In addition, combination therapy with hydralazine and isosorbide dinitrate is recommended in African Americans.

引用

收藏

页码：109 / 123

页数：15

相关论文

共 122 条

[1] Relationship of serum digoxin concentration to mortality and morbidity heart failure in women in the digitalis investigation group trial - A retrospective analysis [J].

Adams, KF ;

Patterson, JH ;

Gattis, WA ;

O'Connor, CM ;

Lee, CR ;

Schwartz, TA ;

Gheorghiade, M .

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2005, 46 (03) :497-504

[2] Digoxin and reduction in mortality and hospitalization in heart failure:: a comprehensive post hoc analysis of the DIG trial [J].

Ahmed, A ;

Rich, MW ;

Love, TE ;

Lloyd-Jones, DM ;

Aban, IB ;

Colucci, WS ;

Adams, KF ;

Gheorghiade, M .

EUROPEAN HEART JOURNAL, 2006, 27 (02) :178-186

[3]

Ahmed A, 2006, CIRCULATION, V114, P115

[4] Heart failure, chronic diuretic use, and increase in mortality and hospitalization: an observational study using propensity score methods [J].

Ahmed, Ali ;

Husain, Ahsan ;

Love, Thomas E. ;

Gambassi, Giovanni ;

Dell'Italia, Louis J. ;

Francis, Gary S. ;

Gheorghiade, Mihai ;

Allman, Richard M. ;

Meleth, Sreelatha ;

Bourge, Robert C. .

EUROPEAN HEART JOURNAL, 2006, 27 (12) :1431-1439

[5] Prolonged impairment of regional contractile function after resolution of exercise-induced angina - Evidence of myocardial stunning in patients with coronary artery disease [J].

Ambrosio, G ;

Betocchi, S ;

Pace, L ;

Losi, MA ;

PerroneFilardi, P ;

Soricelli, A ;

Piscione, F ;

Taube, J ;

Squame, F ;

Salvatore, M ;

Weiss, JL ;

Chiariello, M .

CIRCULATION, 1996, 94 (10) :2455-2464

[6] THE EFFECT OF THE ANGIOTENSIN-CONVERTING ENZYME-INHIBITOR ZOFENOPRIL ON MORTALITY AND MORBIDITY AFTER ANTERIOR MYOCARDIAL-INFARCTION [J].

AMBROSIONI, E ;

BORGHI, C ;

MAGNANI, B .

NEW ENGLAND JOURNAL OF MEDICINE, 1995, 332 (02) :80-85

[7] Inflammatory mediators in chronic heart failure: An overview [J].

Anker, SD ;

von Haehling, S .

HEART, 2004, 90 (04) :464-470

[8]

[Anonymous], 2005, HEART DIS STROKE STA

[9] Diastolic heart failure [J].

Maurer, MS ;

Packer, M ;

Burkhoff, D .

NEW ENGLAND JOURNAL OF MEDICINE, 2004, 351 (11) :1143-1143

[10]

BALL SG, 1993, LANCET, V342, P821

← 1 2 3 4 5 6 7 8 9 10 →