Mailborne transmission of anthrax: Modeling and implications

被引:34
作者
Webb, GF [1 ]
Blaser, MJ
机构
[1] Vanderbilt Univ, Dept Math, Nashville, TN 37235 USA
[2] NYU, Sch Med, Dept Med & Microbiol, New York, NY 10016 USA
[3] Vet Adm Med Ctr, New York, NY 10016 USA
关键词
D O I
10.1073/pnas.102691499
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 [理学]; 0710 [生物学]; 09 [农学];
摘要
A mathematical model is developed to analyze the transmission of inhalational anthrax through the postal system by cross-contamination of mail. The model consists of state vectors describing the numbers of cross-contaminated letters generated, the numbers of anthrax spores on these letters, the numbers of resulting infections in recipients, and matrices of transition probabilities acting on these vectors. The model simulates the recent outbreak in the United States, and provides a general framework to investigate the potential impact of possible future outbreaks.
引用
收藏
页码:7027 / 7032
页数:6
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