Synthesis of two naphthoquinone antibiotics, dehydroherbarin and 6-deoxybostrycoidin

被引：49

作者：

Kesteleyn, B ^{[1
]}

De Kimpe, N ^{[1
]}

机构：

[1] State Univ Ghent, Dept Organ Chem, Fac Agr & Appl Biol Sci, B-9000 Ghent, Belgium

来源：

JOURNAL OF ORGANIC CHEMISTRY | 2000年 / 65卷 / 03期

关键词：

D O I：

10.1021/jo990676g

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The synthesis of two naphthoquinone antibiotics, dehydroherbarin (7) and 6-deoxybostrycoidin (5), was accomplished by reaction of 3-acetonyl-2-bromomethyl-6,8-dimethoxy-1,4-naphthoquinone (23) with either triethylamine or ammonia, respectively. This is the first report on their synthesis.

引用

页码：640 / 644

页数：5

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