Absorption, metabolism, and functions of β-cryptoxanthin

被引:137
作者
Burri, Betty J. [1 ]
La Frano, Michael R. [1 ]
Zhu, Chenghao [1 ]
机构
[1] Univ Calif Davis, Western Human Nutr Res Ctr, USDA ARS, Dept Nutr, Davis, CA 95616 USA
关键词
antioxidant; beta-cryptoxanthin; bone; cancer; vitamin A; SERUM CAROTENOID CONCENTRATIONS; SINGLE NUCLEOTIDE POLYMORPHISMS; APOPTOTIC CELL-DEATH; BONE-MINERAL DENSITY; TISSUES IN-VITRO; A POOL SIZE; VITAMIN-A; LUNG-CANCER; FEMORAL TISSUES; MACULAR DEGENERATION;
D O I
10.1093/nutrit/nuv064
中图分类号
R15 [营养卫生、食品卫生]; TS201 [基础科学];
学科分类号
100403 [营养与食品卫生学];
摘要
beta-carotene-rich-Cryptoxanthin, a carotenoid found in fruits and vegetables such as tangerines, red peppers, and pumpkin, has several functions important for human health. Most evidence from observational, in vitro, animal model, and human studies suggests that beta-cryptoxanthin has relatively high bioavailability from its common food sources, to the extent that some beta-cryptoxanthin-rich foods might be equivalent to beta-carotene-rich foods as sources of retinol. beta-Cryptoxanthin is an antioxidant in vitro and appears to be associated with decreased risk of some cancers and degenerative diseases. In addition, many in vitro, animal model, and human studies suggest that beta-cryptoxanthin-rich foods may have an anabolic effect on bone and, thus, may help delay osteoporosis.
引用
收藏
页码:69 / 82
页数:14
相关论文
共 162 条
[1]
Plasma carotenoids as biomarkers of intake of fruits and vegetables:: ecological-level correlations in the European Prospective Investigation into Cancer and Nutrition (EPIC) [J].
Al-Delaimy, WK ;
Slimani, N ;
Ferrari, P ;
Key, T ;
Spencer, E ;
Johansson, I ;
Johansson, G ;
Mattisson, I ;
Wirfalt, E ;
Sieri, S ;
Agudo, A ;
Celentano, E ;
Palli, D ;
Sacerdote, C ;
Tumino, R ;
Dorronsoro, M ;
Ocké, MC ;
Bueno-De-Mesquita, HB ;
Overvad, K ;
Chirlaque, MD ;
Trichopoulou, A ;
Naska, A ;
Tjonneland, A ;
Olsen, A ;
Lund, E ;
Skeie, G ;
Ardanaz, E ;
Kesse, E ;
Boutron-Ruault, MC ;
Clavel-Chapelon, F ;
Bingham, S ;
Welch, AA ;
Martinez-Garcia, C ;
Nagel, G ;
Linseisen, J ;
Quirós, JR ;
Peeters, PHM ;
van Gils, CH ;
Boeing, H ;
van Kappel, AL ;
Steghens, JP ;
Riboli, E .
EUROPEAN JOURNAL OF CLINICAL NUTRITION, 2005, 59 (12) :1397-1408
[2]
alpha-tocopherol and beta-carotene supplements and lung cancer incidence in the Alpha-Tocopherol, Beta-Carotene Cancer Prevention Study: Effects of base-line characteristics and study compliance [J].
Albanes, D ;
Heinonen, OP ;
Taylor, PR ;
Virtamo, J ;
Edwards, BK ;
Rautalahti, M ;
Hartman, AM ;
Palmgren, J ;
Freedman, LS ;
Haapakoski, J ;
Barrett, MJ ;
Pietinen, P ;
Malila, N ;
Tala, E ;
Liippo, K ;
Salomaa, ER ;
Tangrea, JA ;
Teppo, L ;
Askin, FB ;
Taskinen, E ;
Erozan, Y ;
Greenwald, P ;
Huttunen, JK .
JOURNAL OF THE NATIONAL CANCER INSTITUTE, 1996, 88 (21) :1560-1570
[3]
Two Carotenoid Oxygenases Contribute to Mammalian Provitamin A Metabolism [J].
Amengual, Jaume ;
Widjaja-Adhi, M. Airanthi K. ;
Rodriguez-Santiago, Susana ;
Hessel, Susanne ;
Golczak, Marcin ;
Palczewski, Krzysztof ;
von Lintig, Johannes .
JOURNAL OF BIOLOGICAL CHEMISTRY, 2013, 288 (47) :34081-34096
[4]
[Anonymous], 2004, VIT MIN REQ HUM NUTR, VSecond
[5]
Age-related Eye Disease Study 2: perspectives, recommendations, and unanswered questions [J].
Aronow, Mary E. ;
Chew, Emily Y. .
CURRENT OPINION IN OPHTHALMOLOGY, 2014, 25 (03) :186-190
[6]
Carotenoid profiles in provitamin A-containing fruits and vegetables affect the bioefficacy in Mongolian gerbils [J].
Arscott, Sara A. ;
Howe, Julie A. ;
Davis, Christopher R. ;
Tanumihardjo, Sherry A. .
EXPERIMENTAL BIOLOGY AND MEDICINE, 2010, 235 (07) :839-848
[7]
Carotenoids and DNA damage [J].
Azqueta, Amaya ;
Collins, Andrew R. .
MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS, 2012, 733 (1-2) :4-13
[8]
Effects of Thermal Processing on the in Vitro Bioaccessibility and Microstructure of β-Carotene in Orange-Fleshed Sweet Potato [J].
Bengtsson, Anton ;
Brackmann, Christian ;
Enejder, Annika ;
Alminger, Marie Larsson ;
Svanberg, Ulf .
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2010, 58 (20) :11090-11096
[9]
Factors Influencing the Chemical Stability of Carotenoids in Foods [J].
Boon, Caitlin S. ;
McClements, D. Julian ;
Weiss, Jochen ;
Decker, Eric A. .
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION, 2010, 50 (06) :515-532
[10]
Human plasma levels of vitamin E and Carotenoids are associated with genetic polymorphisms in genes involved in lipid metabolism [J].
Borel, Patrick ;
Moussa, Myriam ;
Reboul, Emmanuelle ;
Lyan, Bernard ;
Defoort, Catherine ;
Vincent-Baudry, Stephanie ;
Maillot, Matthieu ;
Gastaldi, Marguerite ;
Darmon, Michel ;
Portugal, Henri ;
Planells, Richard ;
Lairon, Denis .
JOURNAL OF NUTRITION, 2007, 137 (12) :2653-2659