Comparative quantitative structure-activity relationship studies on anti-HIV drugs

被引：268

作者：

Garg, R

Gupta, SP ^{[1
]}

Gao, H

Babu, MS

Debnath, AK

Hansch, C

机构：

[1] Pomona Coll, Dept Chem, Claremont, CA 91711 USA

[2] Birla Inst Technol & Sci, Dept Chem, Pilani 333031, Rajasthan, India

[3] Birla Inst Technol & Sci, Dept Pharm, Pilani 333031, Rajasthan, India

[4] Pharmacia & Upjohn Inc, Kalamazoo, MI 49007 USA

[5] Lindsley F Kimball Res Inst, New York Blood Ctr, Biochem Virol Lab, New York, NY 10021 USA

来源：

CHEMICAL REVIEWS | 1999年 / 99卷 / 12期

关键词：

D O I：

10.1021/cr9703358

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

[No abstract available]

引用

页码：3525 / 3601

页数：77

共 197 条

[1] THE USE OF CHARACTERISTIC VOLUMES TO MEASURE CAVITY TERMS IN REVERSED PHASE LIQUID-CHROMATOGRAPHY [J].

ABRAHAM, MH ;

MCGOWAN, JC .

CHROMATOGRAPHIA, 1987, 23 (04) :243-246

[2] Molecular basis of HIV-1 protease drug resistance: Structural analysis of mutant proteases complexed with cyclic urea inhibitors [J].

Ala, PJ ;

Huston, EE ;

Klabe, RM ;

McCabe, DD ;

Duke, JL ;

Rizzo, CJ ;

Korant, BD ;

DeLoskey, RJ ;

Lam, PYS ;

Hodge, CN ;

Chang, CH .

BIOCHEMISTRY, 1997, 36 (07) :1573-1580

[3] KINETIC-STUDIES WITH THE NONNUCLEOSIDE HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1 REVERSE-TRANSCRIPTASE INHIBITOR U-90152E [J].

ALTHAUS, IW ;

CHOU, JJ ;

GONZALES, AJ ;

DEIBEL, MR ;

CHOU, KC ;

KEZDY, FJ ;

ROMERO, DL ;

THOMAS, RC ;

ARISTOFF, PA ;

TARPLEY, WG ;

REUSSER, F .

BIOCHEMICAL PHARMACOLOGY, 1994, 47 (11) :2017-2028

[4] 1,2,3-TRIAZOLE-[2',5'-BIS-O-(TERT-BUTYLDIMETHYLSILYL)-BETA-D-RIBOFURANOSYL]-3'-SPIRO-5''-(4''-AMINO-1'',2''-OXATHIOL 2'',2''-DIOXIDE) (TSAO) ANALOGS - SYNTHESIS AND ANTI-HIV-1 ACTIVITY [J].

ALVAREZ, R ;

VELAZQUEZ, S ;

SANFELIX, A ;

AQUARO, S ;

DECLERCQ, E ;

PERNO, CF ;

KARLSSON, A ;

BALZARINI, J ;

CAMARASA, MJ .

JOURNAL OF MEDICINAL CHEMISTRY, 1994, 37 (24) :4185-4194

[5]

[Anonymous], C QSAR DAT

[6]

Appelt Krzysztof, 1993, Perspectives in Drug Discovery and Design, V1, P23, DOI 10.1007/BF02171654

[7] 2-Sulfonyl-4-chloroanilino moiety: A potent pharmacophore for the anti-human immunodeficiency virus type 1 activity of pyrrolyl aryl sulfones [J].

Artico, M ;

Silvestri, R ;

Massa, S ;

Loi, AG ;

Corrias, S ;

Piras, G ;

LaColla, P .

JOURNAL OF MEDICINAL CHEMISTRY, 1996, 39 (02) :522-530

[8] HIGHLY POTENT AND SELECTIVE-INHIBITION OF HIV-1 REPLICATION BY 6-PHENYLTHIOURACIL DERIVATIVES [J].

BABA, M ;

SHIGETA, S ;

TANAKA, H ;

MIYASAKA, T ;

UBASAWA, M ;

UMEZU, K ;

WALKER, RT ;

PAUWELS, R ;

DECLERCQ, E .

ANTIVIRAL RESEARCH, 1992, 17 (04) :245-264

[9] HIGHLY SPECIFIC-INHIBITION OF HUMAN IMMUNODEFICIENCY VIRUS TYPE-1 BY A NOVEL 6-SUBSTITUTED ACYCLOURIDINE DERIVATIVE [J].

BABA, M ;

TANAKA, H ;

DECLERCQ, E ;

PAUWELS, R ;

BALZARINI, J ;

SCHOLS, D ;

NAKASHIMA, H ;

PERNO, CF ;

WALKER, RT ;

MIYASAKA, T .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1989, 165 (03) :1375-1381

[10] Molecular recognition of protein-ligand complexes: Applications to drug design [J].

Babine, RE ;

Bender, SL .

CHEMICAL REVIEWS, 1997, 97 (05) :1359-1472

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