Zebrafish genomics: From mutants to genes

被引：100

作者：

Postlethwait, JH

Talbot, WS

机构：

[1] NYU,MED CTR,SKIRBALL INST BIOMOL MED,NEW YORK,NY 10016

[2] NYU,MED CTR,DEPT CELL BIOL,NEW YORK,NY 10016

来源：

TRENDS IN GENETICS | 1997年 / 13卷 / 05期

关键词：

D O I：

10.1016/S0168-9525(97)01129-3

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

Exquisite embryonic lethal mutations have been isolated in hundreds of genes necessary for zebrafish development. Analysis of this resource promises to enhance our understanding of the molecular genetic mechanisms of vertebrate development. This review discusses the state of the zebrafish genome project and the genetic trickery that can expedite molecular isolation of genes disrupted by these mutations.

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页码：183 / 190

页数：8

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