Integration of metabolic and mitogenic signal transduction in skeletal muscle

被引：36

作者：

Hawley, JA

Zierath, JR

机构：

[1] RMIT Univ, Sch Med Sci, Exercise Metab Grp, Bundoora, Vic 3083, Australia

[2] Karolinska Inst, Karolinska Hosp, Dept Clin Physiol, S-10401 Stockholm, Sweden

来源：

EXERCISE AND SPORT SCIENCES REVIEWS | 2004年 / 32卷 / 01期

关键词：

5 '-AMP-activated protein kinase; exercise; endurance-training; gene; glycogen; intracellular signaling; mitogen-activated protein kinase; transcription;

D O I：

10.1097/00003677-200401000-00002

中图分类号：

Q4 [生理学];

学科分类号：

071003 [生理学];

摘要：

Exercise has diverse effects on metabolic and mitogenic signaling pathways in human skeletal muscle, implying specificity of intracellular signaling cascades. The role of several parallel signaling cascades are discussed in an effort to assign a physiological role for these targets in the regulation of exercise-mediated responses on metabolism and gene expression.

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页码：4 / 8

页数：5

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