Emergence of multiple drug-resistant human cytomegalovirus variants in 2 patients with human immunodeficiency virus infection unresponsive to highly active antiretroviral therapy

被引：13

作者：

Baldanti, F

Paolucci, S

Parisi, A

Meroni, L

Gerna, G ^{[1
]}

机构：

[1] Policlin San Matteo, IRCCS, Serv Virol, I-27100 Pavia, Italy

[2] Policlin San Matteo, IRCCS, Lab Sperimentali Ric, I-27100 Pavia, Italy

[3] Policlin San Matteo, IRCCS, Div Malattie Infett & Trop, I-27100 Pavia, Italy

[4] Univ Milan, Osped Sacco, Ist Malattie Infett & Trop, Milan, Italy

来源：

CLINICAL INFECTIOUS DISEASES | 2002年 / 34卷 / 08期

基金：

美国国家卫生研究院;

关键词：

D O I：

10.1086/339750

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

In 2 patients infected with human immunodeficiency virus (HIV), highly active antiretroviral therapy was unable to suppress HIV replication as a result of the emergence of drug-resistant HIV variants. Human cytomegalovirus (HCMV) retinitis developed in both patients, and an unusually complex mixture of drug-resistant HCMV variants was detected in both patients.

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收藏

页码：1146 / 1149

页数：4

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