The immunopathogenesis of multiple sclerosis and Guillain-Barre syndrome

被引:56
作者
Giovannoni, G [1 ]
Hartung, HP [1 ]
机构
[1] UNIV WURZBURG, DEPT NEUROL, D-8700 WURZBURG, GERMANY
关键词
D O I
10.1097/00019052-199606000-00004
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
This review covers current hypotheses regarding antigen-specific disease induction, immune responses within the central and peripheral nervous systems, the nonspecific inflammatory cascade, and mechanisms responsible for demyelination, axonal loss, and disease progression in multiple sclerosis and Guillain-Barre syndrome, We also discuss the new evidence on the role of infection as an aetiological factor in multiple sclerosis and Guillain-Barre syndrome.
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收藏
页码:165 / 177
页数:13
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