Sulfadiazine-induced nephrolithiasis in children

被引：23

作者：

Catalano-Pons, C

Bargy, S

Schlecht, D

Tabone, MD

Deschênes, G

Bensman, A

Ulinski, T

机构：

[1] Hop Trousseau, Dept Pediat Nephrol, F-75571 Paris 12, France

[2] Hop Trousseau, Dept Pediat Hematol & Immunol, F-75571 Paris 12, France

来源：

PEDIATRIC NEPHROLOGY | 2004年 / 19卷 / 08期

关键词：

sulfadiazine; nephrolithiasis; acute renal failure; toxoplasmosis;

D O I：

10.1007/s00467-004-1519-8

中图分类号：

R72 [儿科学];

学科分类号：

100202 [儿科学];

摘要：

Sulfadiazine-associated urinary calculi have been described in HIV-positive adult patients but rarely in children. We report two pediatric cases of sulfadiazine-induced nephrolithiasis and review 45 adult cases from the literature. One had a hyper-IgM syndrome and was treated with sulfadiazine for cerebral toxoplasmosis, the other had toxoplasmic retinitis. Both developed multiple bilateral lithiasis with acute renal failure. Normalization of renal function and reduction of calculi size was rapidly achieved after discontinuation of sulfadiazine, hyperhydration, and alkalinization. Bilateral ureteral stents were required in one patient because of anuria.

引用

页码：928 / 931

页数：4

共 28 条

[1]

Sulfadiazine-associated nephrotoxicity in patients with the acquired immunodeficiency syndrome [J].