Hypophosphite mediated carbon-carbon bond formation: total synthesis of epialboatrin and structural revision of alboatrin

被引：67

作者：

Graham, SR ^{[1
]}

Murphy, JA ^{[1
]}

Kennedy, AR ^{[1
]}

机构：

[1] Univ Strathclyde, Dept Pure & Appl Chem, Glasgow G1 1XL, Lanark, Scotland

来源：

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1 | 1999年 / 21期

关键词：

D O I：

10.1039/a907032j

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

1-Ethylpiperidine hypophosphite (1-EPHP) has been used in the key radical-cyclisation step in a B-step synthesis of the phytotoxic metabolite alboatrin and its epimer from orcinol. The synthesis demonstrates that the stereochemistry of the structure initially proposed for alboatrin requires revision.

引用

页码：3071 / 3073

页数：3

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