Chemoenzymatic synthesis of a versatile cyclopentenone: (+)-(3aS,6aS)-2,2-dimethyl-3a beta,6a beta-dihydro-4H-cyclopenta-1,3-dioxol-4-one

被引：17

作者：

Biadatti, T ^{[1
]}

Esker, JL ^{[1
]}

Johnson, CR ^{[1
]}

机构：

[1] WAYNE STATE UNIV,DEPT CHEM,DETROIT,MI 48202

来源：

TETRAHEDRON-ASYMMETRY | 1996年 / 7卷 / 08期

关键词：

D O I：

10.1016/0957-4166(96)00286-8

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

The title cyclopentenone has been prepared by enzymatic resolution of cis-4-phenyloxy- and cis-4-(4-methoxyphenyloxy)-cyclopent-2-en-1-ol in isopropenyl acetate using Pseudomonas cepacia lipase. The use of a 4-methoxyphenyloxy-alcohol intermediate enabled the use of both enzymatically resolved enantiomers in the synthesis of the desired (+)-enone. Copyright (C) 1996 Elsevier Science Ltd

引用

页码：2313 / 2320

页数：8

共 13 条

[1]

ALI SM, 1990, TETRAHEDRON LETT, V31, P1509

[2]

BELANGER P, 1988, TETRAHEDRON LETT, V29, P552

[3] STUDIES ON THE SYNTHESIS OF (-)-NEPLANOCIN-A - HOMOCHIRAL PREPARATION OF A KEY CYCLOPENTANOID INTERMEDIATE [J].