Use of dopamine in the ICU - Hope, hype, belief and facts

被引:12
作者
Girbes, ARJ [1 ]
Smit, AJ [1 ]
机构
[1] UNIV GRONINGEN HOSP,DEPT INTERNAL MED,NL-9700 RB GRONINGEN,NETHERLANDS
关键词
dopamine; ICU; renal circulation; splanchnic circulation; review;
D O I
10.3109/10641969709080815
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
Dopamine is frequently administered in the ICU to critically-ill patients. The widespread use of dopamine does not only involve states of distributive and cardiogenic (imminent) shock, but also prophylaxis for deterioration and/or improvement of kidney- and bowel perfusion. Although many studies have shown an increase of renal- and (in some studies) improvement of splanchnic circulation, well controlled studies have failed to demonstrate a better outcome with respect to renal function and/or survival of prophylactic dopamine administration. Furthermore, evidence exists that norepinephrine is more efficacious in fluid resuscitated septic shock patients to restore blood pressure than dopamine, without jeopardizing the renal function. It is concluded that the widespread use of dopamine in the ICU should be reassessed.
引用
收藏
页码:191 / 199
页数:9
相关论文
共 20 条
[1]  
Aono J, 1994, Masui, V43, P1857
[2]   QUANTITATIVE EFFECTS OF LOW-DOSE DOPAMINE ON URINE OUTPUT IN OLIGURIC SURGICAL INTENSIVE-CARE UNIT PATIENTS [J].
FLANCBAUM, L ;
CHOBAN, PS ;
DASTA, JF .
CRITICAL CARE MEDICINE, 1994, 22 (01) :61-66
[3]   DOPAMINE AND MUCOSAL OXYGENATION IN THE PORCINE JEJUNUM [J].
GERMANN, R ;
HAISJACKL, M ;
HASIBEDER, W ;
SPARR, H ;
LUZ, G ;
PLATTNER, R ;
PERNTHALER, H ;
FRIESENECKER, B ;
FALK, M .
JOURNAL OF APPLIED PHYSIOLOGY, 1994, 77 (06) :2845-2852
[4]  
GIRBES ARJ, 1996, IN PRESS BRIT J ANES
[5]  
GOLDBERG LI, 1972, PHARMACOL REV, V24, P1
[6]   TREATMENT OF CARDIAC AND RENAL EFFECTS OF PEEP WITH DOPAMINE IN PATIENTS WITH ACUTE RESPIRATORY-FAILURE [J].
HEMMER, M ;
SUTER, PM .
ANESTHESIOLOGY, 1979, 50 (05) :399-403
[7]  
KADIEVA VS, 1993, ANESTH ANALG, V76, P362
[8]  
LUNDBERG J, 1990, ANESTH ANALG, V71, P9
[9]  
Lundberg J, 1990, J Cardiothorac Anesth, V4, P348, DOI 10.1016/0888-6296(90)90044-G
[10]   THE CONTRASTING EFFECTS OF DOPAMINE AND NOREPINEPHRINE ON SYSTEMIC AND SPLANCHNIC OXYGEN UTILIZATION IN HYPERDYNAMIC SEPSIS [J].
MARIK, PE ;
MOHEDIN, M .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1994, 272 (17) :1354-1357