Individually resolved DNA molecules stretched and embedded in electrospun polymer nanofibers

被引：40

作者：

Bellan, Leon M. ^{[1
]}

Cross, Joshua D.

Strychalski, Elizabeth A.

Moran-Mirabal, Jose

Craighead, H. G.

机构：

[1] Cornell Univ, Sch Appl & Engn Phys, Ithaca, NY 14853 USA

[2] Cornell Univ, Dept Phys, Ithaca, NY 14853 USA

来源：

NANO LETTERS | 2006年 / 6卷 / 11期

关键词：

D O I：

10.1021/nl061894+

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

We have used the flow characteristics of an electrospinning jet to elongate and fix DNA molecules. We embedded and observed fluorescently labeled lambda bacteriophage DNA molecules in polyethylene oxide nanofibers. The embedded DNA molecules were imaged using fluorescence microscopy and found to be stretched to lengths approaching the full dyed contour length.

引用

页码：2526 / 2530

页数：5

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