Reversible palmitoylation of signaling proteins

被引：230

作者：

Mumby, SM

机构：

[1] Department of Pharmacology, Univ. Texas Southwestern Med. C., Dallas, TX 75235-9041

来源：

CURRENT OPINION IN CELL BIOLOGY | 1997年 / 9卷 / 02期

基金：

美国国家卫生研究院;

关键词：

D O I：

10.1016/S0955-0674(97)80056-7

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Palmitoylation is unique among lipid modifications of proteins in that it is reversible and regulable. Recent advances in the study of palmitoylation include the following: the correlation of this modification with the localization of a signaling protein to specific membrane subdomains; the demonstration of a specific protein-protein interaction that is promoted by palmitoylation; and the identification, characterization, and purification of enzymes catalyzing this modification.

引用

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页码：148 / 154

页数：7

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