One pot synthesis of 4(3H)-quinazolinones

被引：62

作者：

Bhat, BA ^{[1
]}

Sahu, DP ^{[1
]}

机构：

[1] Cent Drug Res Inst, Div Chem Technol, Lucknow 226001, Uttar Pradesh, India

来源：

SYNTHETIC COMMUNICATIONS | 2004年 / 34卷 / 12期

关键词：

4(3H)-quinazolinones; iodine; three-component reaction; one pot synthesis;

D O I：

10.1081/SCC-120038496

中图分类号：

O62 [有机化学];

学科分类号：

070303 [有机化学]; 081704 [应用化学];

摘要：

Anthranilamides undergo cyclocondensation with aldehydes in presence of iodine in a single-pot reaction to afford 2-substituted 4(3H)-quinazolinones in moderate to excellent yield (40-95%). 2,3-Substituted 4(3H)-quinazolinones are synthesized in moderate to good yield by three-component condensation of isotoic anhydride, amine, and aldehyde in presence of iodine.

引用

页码：2169 / 2176

页数：8

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