Smoking among Chinese patients with schizophrenia

被引:39
作者
Chong, SA [1 ]
Choo, HL [1 ]
机构
[1] WOODBRIDGE HOSP, SINGAPORE, SINGAPORE
关键词
D O I
10.3109/00048679609064998
中图分类号
R749 [精神病学];
学科分类号
100205 ;
摘要
Objectives: This study aimed to determine the prevalence of smoking among Chinese with schizophrenia, and to determine if smokers and nonsmokers differ in their age of onset of illness and neuroleptic requirement. Method: One hundred and ninety-five patients were assessed by a single rater using the Brief Psychiatric Rating Scale (BPRS) and the Simpson-Angus Scale. Other historical, demographic and treatment variables were recorded from case records and interviews with patients and family members. Results: A higher rate of smoking was found in patients with schizophrenia than in the general population. There was no significant difference between the smokers and non-smokers in their respective neuroleptic dosages and extrapyramidal side-effects but the smokers had a significantly higher BPRS score. Conclusions: Racial difference is proposed to account for this discrepancy from other Western studies, The contribution of nicotine towards aggravating schizophrenic symptoms is also considered.
引用
收藏
页码:350 / 353
页数:4
相关论文
共 31 条
[1]   EFFECTS OF SINGLE INJECTIONS OF NICOTINE ON THE ASCENDING DOPAMINE PATHWAYS IN THE RAT - EVIDENCE FOR INCREASES OF DOPAMINE TURNOVER IN THE MESOSTRIATAL AND MESOLIMBIC DOPAMINE NEURONS [J].
ANDERSSON, K ;
FUXE, K ;
AGNATI, LF .
ACTA PHYSIOLOGICA SCANDINAVICA, 1981, 112 (03) :345-347
[2]  
[Anonymous], 1987, DIAGNOSTIC STAT MANU, V4th
[3]   PRONOUNCED DIFFERENCES BETWEEN NATIVE CHINESE AND SWEDISH POPULATIONS IN THE POLYMORPHIC HYDROXYLATIONS OF DEBRISOQUIN AND S-MEPHENYTOIN [J].
BERTILSSON, L ;
LOU, YQ ;
DU, YL ;
LIU, Y ;
KUANG, TY ;
LIAO, XM ;
WANG, KY ;
REVIRIEGO, J ;
ISELIUS, L ;
SJOQVIST, F .
CLINICAL PHARMACOLOGY & THERAPEUTICS, 1992, 51 (04) :388-397
[4]  
BINDER RL, 1981, AM J PSYCHIAT, V138, P1243
[5]  
DAVIS JM, 1976, ARCH GEN PSYCHIAT, V33, P858
[6]   CIGARETTE-SMOKING AND NEUROLEPTIC-INDUCED PARKINSONISM [J].
DECINA, P ;
CARACCI, G ;
SANDIK, R ;
BERMAN, W ;
MUKHERJEE, S ;
SCAPICCHIO, P .
BIOLOGICAL PSYCHIATRY, 1990, 28 (06) :502-508
[7]  
DELEON J, 1995, AM J PSYCHIAT, V152, P453
[8]  
DICHIARA G, 1988, P NATL ACAD SCI USA, V85, P5274
[9]  
GARDNER EL, 1992, COMPREHENSIVE TXB SU
[10]  
GLASSMAN AH, 1993, AM J PSYCHIAT, V150, P546