The impact of height and body mass index on the risk of testicular cancer in 600,000 Norwegian men

被引:21
作者
Bjorge, Tone [1 ]
Tretli, Steinar
Lie, A. Kathrine
Engeland, Anders
机构
[1] Univ Bergen, Dept Publ Hlth & Primary Hlth Care, Sect Epidemiol & Med Stat, N-5018 Bergen, Norway
[2] Norwegian Inst Publ Hlth, Div Epidemiol, N-0403 Oslo, Norway
[3] Canc Registry Norway, Inst Populat Based Canc Res, N-0310 Oslo, Norway
关键词
body mass index; testicular cancer; germ cell tumors; cohort study; Norway;
D O I
10.1007/s10552-006-0032-8
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
The present study aimed at exploring the relations between body mass index (BMI) and stature and testicular cancer in a huge Norwegian cohort with measured height and weight. Height and weight were measured in 600,000 Norwegian men aged 14-44 years during 1963-2001. Results from parts of the study cohort have been reported previously. During follow-up, 1,357 testicular cancers were registered. Relative risks (RRs) of testicular cancer were estimated using Cox proportional hazards regression. The risk of testicular cancer decreased with adult BMI. Compared with men with normal BMI, overweight and obese men had a relative risk of cancer of 0.89 (95% CI: 0.77-1.03) and 0.83 (95% CI: 0.58-1.17). The relative risk of testicular cancer per unit increase in BMI was 0.97 (95% CI: 0.95-1.00). The risk of testicular cancer was not associated with adolescent BMI. A moderate increase in risk of seminomas was seen with increasing adult height. Compared with men with height 170-79 cm, men with height 180 cm and above had a relative risk of 1.17 (95% CI: 1.00-1.37).
引用
收藏
页码:983 / 987
页数:5
相关论文
共 19 条
[1]   Body size and testicular cancer [J].
Akre, O ;
Ekbom, A ;
Sparén, P ;
Tretli, S .
JOURNAL OF THE NATIONAL CANCER INSTITUTE, 2000, 92 (13) :1093-1096
[2]  
Bjartveit K, 1979, Acta Med Scand Suppl, V634, P1
[3]  
Bjartveit K, 1997, NOR EPIDEMIOL, V7, P157
[4]   Relation of height and body mass index to renal cell carcinoma in two million Norwegian men and women [J].
Bjorge, T ;
Tretli, S ;
Engeland, A .
AMERICAN JOURNAL OF EPIDEMIOLOGY, 2004, 160 (12) :1168-1176
[5]   Secular trends in growth [J].
Cole, TJ .
PROCEEDINGS OF THE NUTRITION SOCIETY, 2000, 59 (02) :317-324
[6]  
Cox D. R., 1984, Analysis of survival data
[7]   Clinical epidemiology of testicular germ cell tumors [J].
Dieckmann, KP ;
Pichlmeier, U .
WORLD JOURNAL OF UROLOGY, 2004, 22 (01) :2-14
[8]   Is risk of testicular cancer related to body size? [J].
Dieckmann, KP ;
Pichlmeier, U .
EUROPEAN UROLOGY, 2002, 42 (06) :564-569
[9]  
Grummer-Strawn, 2000, ADV DATA, V8, P1
[10]  
IARC Working Group on the Evaluation of Cancer-Preventive Strategies, 2002, WEIGHT CONTR PHYS AC