Synthesis of tertiary propargylamines by sequential reactions of in situ generated thioiminium salts with organolithium and -magnesium reagents

被引：188

作者：

Murai, T ^{[1
]}

Mutoh, Y

Ohta, Y

Murakami, M

机构：

[1] Gifu Univ, Fac Engn, Dept Chem, Gifu 5011193, Japan

[2] Kyoto Univ, Dept Synthet Chem & Biol Chem, Kyoto 6158510, Japan

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2004年 / 126卷 / 19期

关键词：

D O I：

10.1021/ja048627v

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Sequential reactions of thioiminium salts generated from thioamides and methyl triflate with organolithium and -magnesium reagents proceed smoothly to give tertiary propargylamines in moderate to high yields. In all cases, two different organometallic reagents are incorporated into the starting thioamides. Copyright © 2003 American Chemical Society.

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页码：5968 / 5969

页数：2

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