Biomechanical Perspective on the Remineralization of Dentin

被引:182
作者
Bertassoni, L. E. [1 ]
Habelitz, S. [1 ]
Kinney, J. H. [1 ]
Marshall, S. J. [1 ]
Marshall, G. W., Jr. [1 ]
机构
[1] Univ Calif San Francisco, Div Biomat & Bioengn, Dept Prevent & Restorat Dent Sci, San Francisco, CA 94143 USA
关键词
Biomechanics; Caries; Dentin; Mechanical properties; Nanoindentation; Remineralization; TRANSMISSION ELECTRON-MICROSCOPY; MINERALIZED COLLAGEN FIBRILS; DEMINERALIZED HUMAN DENTIN; X-RAY-SCATTERING; MECHANICAL-PROPERTIES; CARIOUS DENTIN; CARIES LESIONS; ROOT CARIES; IN-VITRO; BONE;
D O I
10.1159/000201593
中图分类号
R78 [口腔科学];
学科分类号
100302 [口腔临床医学];
摘要
The objective of this article is to critically evaluate the methods that are used to assess outcomes of remineralization of dentin. Currently, the most used assessment methods fall either into quantitative analysis of the mineral content of the remineralized structures or dry measurements of their mechanical properties. Properties obtained from the dehydrated organic dentin matrix may not reflect the true mechanical behavior of the remineralized tissue under physiological and hydrated conditions. Here we seek to clarify the biomechanical aspects of remineralization of dentin, pointing out the effects of hydration and dehydration on the mechanical properties of treated tissues. We also emphasize that a more appropriate endpoint to evaluate the effectiveness of remineralization in dentin should be associated with the recovery of the mechanical properties of the hydrated tissue, which is presumed to correlate well with its overall functionality. Copyright (C) 2009 S. Karger AG, Basel
引用
收藏
页码:70 / 77
页数:8
相关论文
共 63 条
[1]
Influence of hydration and mechanical characterization of carious primary dentine using an ultra-micro indentation system (UMIS) [J].
Angker, L ;
Nijhof, N ;
Swain, MV ;
Kilpatrick, NM .
EUROPEAN JOURNAL OF ORAL SCIENCES, 2004, 112 (03) :231-236
[2]
DEMINERALIZATION AND REMINERALIZATION EVALUATION TECHNIQUES [J].
ARENDS, J ;
TENBOSCH, JJ .
JOURNAL OF DENTAL RESEARCH, 1992, 71 :924-928
[3]
Arends J, 1997, Adv Dent Res, V11, P403
[4]
Micromorphological and micronanalytical characterization of stagnating and progressing root caries lesions [J].
Arnold, Wolfgang H. ;
Bietau, Vera ;
Renner, Philipp O. ;
Gaengler, Peter .
ARCHIVES OF ORAL BIOLOGY, 2007, 52 (06) :591-597
[5]
Age, dehydration and fatigue crack growth in dentin [J].
Bajaj, D ;
Sundaram, N ;
Nazari, A ;
Arola, D .
BIOMATERIALS, 2006, 27 (11) :2507-2517
[6]
Mechanical properties of mineralized collagen fibrils as influenced by demineralization [J].
Balooch, M. ;
Habelitz, S. ;
Kinney, J. H. ;
Marshall, S. J. ;
Marshall, G. W. .
JOURNAL OF STRUCTURAL BIOLOGY, 2008, 162 (03) :404-410
[7]
Balooch M, 1998, J BIOMED MATER RES, V40, P539, DOI 10.1002/(SICI)1097-4636(19980615)40:4<539::AID-JBM4>3.0.CO
[8]
2-G
[9]
Infrared spectroscopic characterization of mineralized tissues [J].
Boskey, AL ;
Mendelsohn, R .
VIBRATIONAL SPECTROSCOPY, 2005, 38 (1-2) :107-114
[10]
BOYDE A, 1974, CELL TISSUE RES, V152, P543