Multiple approaches to multiple sclerosis

被引：22

作者：

Steinman, L ^{[1
]}

机构：

[1] Stanford Univ, Beckman Ctr Mol Med, Dept Neurol & Neurol Sci, Stanford, CA 94305 USA

来源：

NATURE MEDICINE | 2000年 / 6卷 / 01期

关键词：

D O I：

10.1038/71466

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Multiple sclerosis results from the failure of several different regulatory mechanisms designed to protect against autoimmunity, suggesting multiple targets for therapeutic intervention. Three papers in this issue suggest that if tolerance to components of the nervous system is not maintained in the thymus and autoimmunity ensues, the extent of brain damage can be checked by blockade of glutamate receptors on neurons and oligodendrocytes (pages 56-70).

引用

页码：15 / 16

页数：2

共 10 条

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