From mono- to oligo-Smads:: The heart of the matter in TGF-β signal transduction

被引:72
作者
Moustakas, A [1 ]
Heldin, CH [1 ]
机构
[1] Ludwig Inst Canc Res, SE-75124 Uppsala, Sweden
关键词
D O I
10.1101/gad.1016802
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
[No abstract available]
引用
收藏
页码:1867 / 1871
页数:5
相关论文
共 27 条
[1]   Signal transduction by the TGF-β superfamily [J].
Attisano, L ;
Wrana, JL .
SCIENCE, 2002, 296 (5573) :1646-1647
[2]   The L3 loop and C-terminal phosphorylation jointly define Smad protein trimerization [J].
Chacko, BM ;
Qin, B ;
Correia, JJ ;
Lam, SS ;
de Caestecker, MP ;
Lin, K .
NATURE STRUCTURAL BIOLOGY, 2001, 8 (03) :248-253
[3]   Sedimentation studies reveal a direct role of phosphorylation in Smad3:Smad4 homo- and hetero-trimerization [J].
Correia, JJ ;
Chacko, BM ;
Lam, SS ;
Lin, K .
BIOCHEMISTRY, 2001, 40 (05) :1473-1482
[4]   Multivalent endosome targeting by homodimeric EEA1 [J].
Dumas, JJ ;
Merithew, E ;
Sudharshan, E ;
Rajamani, D ;
Hayes, S ;
Lawe, D ;
Corvera, S ;
Lambright, DG .
MOLECULAR CELL, 2001, 8 (05) :947-958
[5]   The TGFβ receptor activation process:: An inhibitor- to substrate-binding switch [J].
Huse, M ;
Muir, TW ;
Xu, L ;
Chen, YG ;
Kuriyan, J ;
Massagué, J .
MOLECULAR CELL, 2001, 8 (03) :671-682
[6]   The FYVE domain in Smad anchor for receptor activation (SARA) is sufficient for localization of SARA in early endosomes and regulates TGF-β/Smad signalling [J].
Itoh, F ;
Divecha, N ;
Brocks, L ;
Oomen, L ;
Janssen, H ;
Calafat, J ;
Itoh, S ;
ten Dijke, P .
GENES TO CELLS, 2002, 7 (03) :321-331
[7]   Distinct oligomeric states of SMAD proteins in the transforming growth factor-β pathway [J].
Jayaraman, L ;
Massagué, J .
JOURNAL OF BIOLOGICAL CHEMISTRY, 2000, 275 (52) :40710-40717
[8]  
Kirsch T, 2000, NAT STRUCT BIOL, V7, P492
[9]   Ski/Sno and TGF-β signaling [J].
Liu, XD ;
Sun, Y ;
Weinberg, RA ;
Lodish, HF .
CYTOKINE & GROWTH FACTOR REVIEWS, 2001, 12 (01) :1-8
[10]  
LU Z, 2002, IN PRESS J BIOL CHEM