Nanotechnology and biosensors

被引:520
作者
Chen, JR
Miao, YQ [1 ]
He, NY
Wu, XH
Li, SJ
机构
[1] Zhejiang Normal Univ, Coll Chem & Life Sci, Jinhua 321004, Peoples R China
[2] Southeast Univ, Chien Shiung Wu Lab, Nanjing 210096, Peoples R China
关键词
biosensors; nanotechnology; nanomaterials; nanostructure; nano-electromechanical systems (NEMS); self-assembly;
D O I
10.1016/j.biotechadv.2004.03.004
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 [微生物学]; 0836 [生物工程]; 090102 [作物遗传育种]; 100705 [微生物与生化药学];
摘要
Nanotechnology is playing an increasingly important role in the development of biosensors. The sensitivity and performance of biosensors is being improved by using nanomaterials for their construction. The use of these nanomaterials has allowed the introduction of many new signal transduction technologies in biosensors. Because of their submicron dimensions, nanosensors, nanoprobes and other nanosystems have allowed simple and rapid analyses in vivo. Portable instruments capable of analyzing multiple components are becoming available. This work reviews the status of the various nanostructure-based biosensors. Use of the self-assembly techniques and nano-electromechanical systems (NEMS) in biosensors is discussed. (C) 2004 Elsevier Inc. All rights reserved.
引用
收藏
页码:505 / 518
页数:14
相关论文
共 63 条
[1]
AMTZ Y, 2003, NANOTECHNOLOGY, V14, P86
[2]
Bioelectrochemical single-walled carbon nanotubes [J].
Azamian, BR ;
Davis, JJ ;
Coleman, KS ;
Bagshaw, CB ;
Green, MLH .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2002, 124 (43) :12664-12665
[3]
RNA biosensor for the rapid detection of viable Escherichia coli in drinking water [J].
Baeumner, AJ ;
Cohen, RN ;
Miksic, V ;
Min, JH .
BIOSENSORS & BIOELECTRONICS, 2003, 18 (04) :405-413
[4]
Biosensor based on force microscope technology [J].
Baselt, DR ;
Lee, GU ;
Colton, RJ .
JOURNAL OF VACUUM SCIENCE & TECHNOLOGY B, 1996, 14 (02) :789-793
[5]
Bauer G, 1999, MIKROCHIM ACTA, V131, P107, DOI 10.1007/s006040050015
[6]
Surface functionalization for self-referencing surface plasmon resonance (SPR) biosensors by multi-step self-assembly [J].
Boozer, C ;
Yu, QM ;
Chen, SF ;
Lee, CY ;
Homola, J ;
Yee, SS ;
Jiang, SY .
SENSORS AND ACTUATORS B-CHEMICAL, 2003, 90 (1-3) :22-30
[7]
Colloid Au-enhanced DNA immobilization for the electrochemical detection of sequence-specific DNA [J].
Cai, H ;
Xu, C ;
He, PG ;
Fang, YZ .
JOURNAL OF ELECTROANALYTICAL CHEMISTRY, 2001, 510 (1-2) :78-85
[8]
Chan S, 2000, PHYS STATUS SOLIDI A, V182, P541, DOI 10.1002/1521-396X(200011)182:1<541::AID-PSSA541>3.0.CO
[9]
2-#
[10]
Ultrasensitive magnetic biosensor for homogeneous immunoassay [J].
Chemla, YR ;
Crossman, HL ;
Poon, Y ;
McDermott, R ;
Stevens, R ;
Alper, MD ;
Clarke, J .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2000, 97 (26) :14268-14272