Multivariate logistic models for incomplete binary responses

被引:62
作者
Fitzmaurice, GM
Laird, NM
Zahner, GEP
机构
[1] HARVARD UNIV,SCH PUBL HLTH,DEPT BIOSTAT,BOSTON,MA 02115
[2] HARVARD UNIV,SCH PUBL HLTH,DEPT EPIDEMIOL,BOSTON,MA 02115
关键词
binary response; EM algorithm; marginal models; missing data;
D O I
10.2307/2291386
中图分类号
O21 [概率论与数理统计]; C8 [统计学];
学科分类号
020208 ; 070103 ; 0714 ;
摘要
In this article we describe a likelihood-based regression model appropriate for analyzing incomplete multivariate binary responses. We focus on ''marginal models''; that is, models where the marginal mean or expectation of the binary response is related to a set of covariates. The association between the binary responses is modeled in terms of conditional log odds ratios. When the nonresponse mechanism is ignorable, it is not necessary to specify a nonresponse model, and valid inferences can be obtained provided that the likelihood for the responses has been correctly specified. But when the nonresponse mechanism is nonignorable, valid inferences can only be obtained by incorporating a model for nonresponse. An unresolved issue with nonignorable models concerns the identifiability of the parameters. So far, no general and practically useful necessary and sufficient conditions for identifiability are available. Here we suggest some simple procedures for examining the identifiability status of nonignorable models when the response variable is discrete. Finally, we present results for an analysis of multiple informant data from the New Haven Child Survey and the Eastern Connecticut Child Survey.
引用
收藏
页码:99 / 108
页数:10
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