Characterization of plasmids carrying CMY-2 from expanded-spectrum cephalosporin-resistant Salmonella strains isolated in the United States between 1996 and 1998

被引：124

作者：

Carattoli, A

Tosini, F

Giles, WP

Rupp, ME

Hinrichs, SH

Angulo, FJ

Barrett, TJ

Fey, PD

机构：

[1] Ist Super Sanita, Lab Bacteriol & Mycol, I-00161 Rome, Italy

[2] Ist Super Sanita, Lab Cellular Biol, I-00161 Rome, Italy

[3] Univ Nebraska, Med Ctr, Dept Internal Med, Omaha, NE USA

[4] Univ Nebraska, Med Ctr, Dept Pathol & Microbiol, Nebraska Publ Hlth Lab, Omaha, NE USA

[5] CDCP, Foodborne & Diarrheal Dis Branch, Div Bacterial & Mycot Dis, Natl Ctr Infect Dis, Atlanta, GA USA

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2002年 / 46卷 / 05期

关键词：

D O I：

10.1128/AAC.46.5.1269-1272.2002

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Sequencing of DNA from 15 expanded-spectrum cephalosporin (e.g., ceftriaxone)-resistant Salmonella isolates obtained in the United States revealed that resistance to ceftriaxone in all isolates was mediated by cmy-2. Hybridization patterns revealed three plasmid structures containing cmy-2 in these 15 isolates. These data suggest that the spread of cmy-2 among Salmonella strains is occurring through mobilization of the cmy-2 gene into different plasmid backbones and consequent horizontal transfer by conjugation.

引用

页码：1269 / 1272

页数：4

共 21 条

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