Planar chiral ferrocenes as ligands in the vanadium-catalyzed asymmetric epoxidation of allylic alcohols

被引：12

作者：

Bolm, C ^{[1
]}

Kühn, T ^{[1
]}

机构：

[1] Rhein Westfal TH Aachen, Inst Organ Chem, D-52056 Aachen, Germany

来源：

ISRAEL JOURNAL OF CHEMISTRY | 2001年 / 41卷 / 04期

关键词：

D O I：

10.1092/YMYD-FF4Y-MB9C-EFTE

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Starting from either (S)-4-tert-butyl-2-ferrocenyl-2-oxazoline or (S)-S-ferrocenyl-S-4-tolyl sulfoxide, new planar chiral hydroxamic acids have been synthesized employing the directed ortho-metalation strategy. The ferrocene-derived hydroxamic acids are capable of serving as ligands in the vanadium-catalyzed asymmetric epoxidation of allylic alcohols, furnishing the epoxide of 2-methyl-3-phenylprop-2-en-1-ol with up to 34% ee.

引用

页码：263 / 269

页数：7

共 53 条

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