A new palladium catalyst system for the cyanation of aryl chlorides with K4[Fe(CN)6]

被引：148

作者：

Schareina, Thomas

Zapf, Alexander

Maegerlein, Wolfgang

Mueller, Nikolaus

Beller, Matthias

机构：

[1] Univ Rostock, Leibniz Inst Katalyse eV, D-18059 Rostock, Germany

[2] Saltigo GmbH, D-51369 Leverkusen, Germany

来源：

TETRAHEDRON LETTERS | 2007年 / 48卷 / 07期

关键词：

D O I：

10.1016/j.tetlet.2006.12.087

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The development of a novel Pd-catalyzed synthesis of (hetero)aromatic nitrites from the corresponding aryl chlorides and potassium hexacyanoferrate(II) is described. This novel protocol avoids the use of highly toxic alkali cyanides and proceeds in the presence of small amounts of palladium catalysts. High yields and selectivities of the corresponding aryl nitriles were achieved applying di(1-adamantyl)-1-butylphosphine (cataCXium((R)) A) as the ligand. (c) 2006 Elsevier Ltd. All rights reserved.

引用

页码：1087 / 1090

页数：4

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