Quantitative trait loci associated with fatness in a broiler-layer cross

被引:36
作者
Campos, R. L. R.
Nones, K.
Ledur, M. C. [2 ]
Moura, A. S. A. M. T. [3 ]
Pinto, L. F. B.
Ambo, M.
Boschiero, C. [3 ]
Ruy, D. C.
Baron, E. E.
Ninov, K. [2 ]
Altenhofen, C. A. B. [2 ]
Silva, R. A. M. S. [2 ]
Rosario, M. F.
Burt, D. W. [4 ,5 ]
Coutinho, L. L. [1 ]
机构
[1] USP, ESALQ, Lab Biotecnol Anim, Dept Zootecnia, BR-13418900 Piracicaba, SP, Brazil
[2] Embrapa Suinos & Aves, BR-89700000 Concordia, SC, Brazil
[3] UNESP, FMVZ, Dept Anim Prod, BR-18618000 Botucatu, SP, Brazil
[4] Roslin Inst, Dept Genet & Genom, Roslin EH25 9PS, Midlothian, Scotland
[5] Royal Dick Sch Vet Studies, Roslin EH25 9PS, Midlothian, Scotland
基金
巴西圣保罗研究基金会;
关键词
abdominal fat; broiler; chicken; imprinting; layer; BRAZILIAN RESOURCE POPULATION; ABDOMINAL FAT WEIGHT; MEAT QUALITY TRAITS; CHICKEN LINES; BODY-COMPOSITION; CARCASS TRAITS; MUSCLE MASS; IGF2; LOCUS; QTL; GROWTH;
D O I
10.1111/j.1365-2052.2009.01910.x
中图分类号
S8 [畜牧、 动物医学、狩猎、蚕、蜂];
学科分类号
0905 ;
摘要
P>An F-2 population established by crossing a broiler male line and a layer line was used to map quantitative trait loci (QTL) affecting abdominal fat weight, abdominal fat percentage and serum cholesterol and triglyceride concentrations. Two genetic models, the line-cross and the half-sib, were applied in the QTL analysis, both using the regression interval method. Three significant QTL and four suggestive QTL were mapped in the line-cross analysis and four significant and four suggestive QTL were mapped in the half-sib analysis. A total of five QTL were mapped for abdominal fat weight, six for abdominal fat percentage and four for triglyceride concentration in both analyses. New QTL associated with serum triglyceride concentration were mapped on GGA5, GGA23 and GG27. QTL mapped between markers LEI0029 and ADL0371 on GGA3 for abdominal fat percentage and abdominal fat weight and a suggestive QTL on GGA12 for abdominal fat percentage showed significant parent-of-origin effects. Some QTL mapped here match QTL regions mapped in previous studies using different populations, suggesting good candidate regions for fine-mapping and candidate gene searches.
引用
收藏
页码:729 / 736
页数:8
相关论文
共 39 条
[1]   Genome-wide association analysis reveals cryptic alleles as an important factor in heterosis for fatness in chicken F2 population [J].
Abasht, B. ;
Lamont, S. J. .
ANIMAL GENETICS, 2007, 38 (05) :491-498
[2]   Review of quantitative trait loci identified in the chicken [J].
Abasht, B. ;
Dekkers, J. C. M. ;
Lamont, S. J. .
POULTRY SCIENCE, 2006, 85 (12) :2079-2096
[3]   Genetic linkage maps of chicken chromosomes 6, 7, 8, 11 and 13 from a Brazilian resource population [J].
Ambo, Marcel ;
Rocha Campos, Raquel de Lello ;
Meira Tavares Moura, Ana Silvia ;
Boschiero, Clarissa ;
do Rosario, Millor Fernandes ;
Ledur, Monica Correa ;
Nones, Katia ;
Coutinho, Luiz Lehmann .
SCIENTIA AGRICOLA, 2008, 65 (05) :447-452
[4]   Investigation of two candidate genes for meat quality traits in a quantitative trait locus region on SSC6:: the porcine short heterodimer partner and heart fatty acid binding protein genes [J].
Arnyasi, M. ;
Grindflek, E. ;
Javor, A. ;
Lien, S. .
JOURNAL OF ANIMAL BREEDING AND GENETICS, 2006, 123 (03) :198-203
[5]   QTLs associated with growth traits and abdominal fat weight and their interactions with gender and hatch in commercial meat-type chickens [J].
Atzmon, G. ;
Ronin, Y. I. ;
Korol, A. ;
Yonash, N. ;
Cheng, H. ;
Hillel, J. .
ANIMAL GENETICS, 2006, 37 (04) :352-358
[6]  
CHOCT M, 2000, PUBLICATION RURAL IN
[7]  
CHURCHILL GA, 1994, GENETICS, V138, P963
[8]  
de Koning DJ, 2002, GENETICS, V161, P931
[9]   GENOTYPIC CHARACTERIZATION OF MICROSATELLITE MARKERS IN BROILER AND LAYER SELECTED CHICKEN LINES AND THEIR RECIPROCAL F1s [J].
do Rosario, Millor Fernandes ;
Ledur, Monica Correa ;
Meira Tavares Moura, Ana Silvia Alves ;
Coutinho, Luiz Lehmann ;
Franco Garcia, Antonio Augusto .
SCIENTIA AGRICOLA, 2009, 66 (02) :150-158
[10]   Chicken orthologues of mammalian imprinted genes are clustered on macrochromosomes and replicate asynchronously [J].
Dünzinger, U ;
Nanda, I ;
Schmid, M ;
Haaf, T ;
Zechner, U .
TRENDS IN GENETICS, 2005, 21 (09) :488-492