Monoclonal antibody manufacturing in transgenic plants - myths and realities

被引：102

作者：

Hood, EE ^{[1
]}

Woodard, SL ^{[1
]}

Horn, ME ^{[1
]}

机构：

[1] ProdiGene Inc, College Stn, TX 77845 USA

来源：

CURRENT OPINION IN BIOTECHNOLOGY | 2002年 / 13卷 / 06期

关键词：

D O I：

10.1016/S0958-1669(02)00351-8

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

The number and types of antibodies expressed in plants has increased steadily since the first reports of this accomplishment in the 1980s, illustrating the versatility of plants as a production system for antibodies. Many recent reviews have detailed the antibody forms that have been derived from plant expression systems. This contribution focuses on the remaining challenges to develop plant-derived therapeutic antibodies into products, and some of the progress that is being made in addressing these challenges.

引用

页码：630 / 635

页数：6

共 19 条

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