Magnetic hydroxyapatite/chitosan nanocomposites via in situ hybridization strategy

被引:1
作者
Li, Baoqiang [1 ]
Jia, Dechang [1 ]
Zhou, Yu [1 ]
Hu, Qiaoling [2 ]
Cai, Wei [3 ]
机构
[1] Harbin Inst Technol, Inst Adv Ceram, Harbin 150001, Peoples R China
[2] Zhejiang Univ, Inst Polymer Composite, Hangzhou 310027, Peoples R China
[3] Harbin Inst Technol, Mat Chem & Phys, Harbin 150001, Peoples R China
来源
BIOCERAMICS, VOL 19, PTS 1 AND 2 | 2007年 / 330-332卷
关键词
chitosan; hydroxyapatite; in situ hybridization; magnetite; hyperthermia;
D O I
10.4028/www.scientific.net/KEM.330-332.357
中图分类号
TQ174 [陶瓷工业]; TB3 [工程材料学];
学科分类号
0805 [材料科学与工程]; 080502 [材料学];
摘要
Magnetic hydroxyapatite/chitosan nanocomposites were prepared via in situ hybridization strategy in the ambient condition. Magnetic hydroxyapatite/chitosan nanocomposites were investigated by XRD, SQUID and TEM. XRD results indicated that the inorganic phases dispersed in chitosan matrix were composed of magnetite and hydroxyapatite. The magnetic hydroxyapatite/chitosan shown the behavior of superparamagnetism determined by SQUID, which indicated the size of magnetite crystal were less than 30nm. The inorganic nanoparticles with size of 30-50nm were dispersed chitosan matrix homogeneously. In situ hybridization strategy provided a simple and efficient route to synthesize the magnetic chitosan/hydroxyapatite nanocomposites in the mild condition. The most important of in situ hybridization is that the processes of precipitation of chitosan, synthesis of magnetite and hydroxyapatitc, and compositing between three components were completed in single step.
引用
收藏
页码:357 / +
页数:2
相关论文
共 7 条
[1]
Einhorn TA, 2004, OSTEOPOROSIS INT, V15, pS2
[2]
Preparation and characterization of biodegradable chitosan/hydroxyapatite nanocomposite rods via in situ hybridization: A potential material as internal fixation of bone fracture [J].
Hu, QL ;
Li, BQ ;
Wang, M ;
Shen, JC .
BIOMATERIALS, 2004, 25 (05) :779-785
[3]
Tissue engineering of bone: effects of mechanical strain on osteoblastic cells in type I collagen matrices [J].
Ignatius, A ;
Blessing, H ;
Liedert, A ;
Schmidt, C ;
Neidlinger-Wilke, C ;
Kaspar, D ;
Friemert, B ;
Claes, L .
BIOMATERIALS, 2005, 26 (03) :311-318
[4]
Magnetic orientation of collagen and bone mixture [J].
Kotani, H ;
Iwasaka, M ;
Ueno, S ;
Curtis, A .
JOURNAL OF APPLIED PHYSICS, 2000, 87 (09) :6191-6193
[5]
Release of a chitosan-hydroxyapatite composite loaded with ibuprofen and acetyl-salicylic acid submitted to different sterilization treatments [J].
Larena, A ;
Cáceres, DA ;
Vicario, C ;
Fuentes, A .
APPLIED SURFACE SCIENCE, 2004, 238 (1-4) :518-522
[6]
Magnetic nanoparticle design for medical diagnosis and therapy [J].
Mornet, S ;
Vasseur, S ;
Grasset, F ;
Duguet, E .
JOURNAL OF MATERIALS CHEMISTRY, 2004, 14 (14) :2161-2175
[7]
Influence of magnetic field on the growth and properties of calcium tartrate crystals [J].
Saban, KV ;
Jini, T ;
Varghese, G .
JOURNAL OF MAGNETISM AND MAGNETIC MATERIALS, 2003, 265 (03) :296-304