Activities of moxifloxacin alone and in combination with other antimicrobial agents against multidrug-resistant Mycobacterium tuberculosis infection in BALB/c mice

被引：39

作者：

Fattorini, L

Tan, DJ

Iona, E

Mattei, M

Giannoni, F

Brunori, L

Recchia, S

Orefici, G

机构：

[1] Ist Super Sanita, Lab Bacteriol & Med Mycol, I-00161 Rome, Italy

[2] Univ Roma Tor Vergata, STA, Dept Biol, Rome, Italy

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2003年 / 47卷 / 01期

关键词：

D O I：

10.1128/AAC.47.1.360-362.2003

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The activity of moxifloxacin was enhanced by the addition of ethionamide but not by that of cycloserine, thiacetazone, capreomycin, para-aminosalicylic acid, or linezolid in BALB/c mice infected with a strain of Mycobacterium tuberculosis resistant to isoniazid, rifampin, and six other drugs. These observations are important for the therapy of multidrug-resistant tuberculosis.

引用

页码：360 / 362

页数：3

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