gp96 leads the way for toll-like receptors

被引：14

作者：

Harding, Clifford V. ^{[1
]}

机构：

[1] Case Western Reserve Univ, Dept Pathol, Cleveland, OH 44106 USA

来源：

IMMUNITY | 2007年 / 26卷 / 02期

关键词：

D O I：

10.1016/j.immuni.2007.02.003

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 [免疫学];

摘要：

The role of the gp96 heat-shock protein in regulating Toll-like-receptor expression is incompletely understood. Yang et al. (2007) generated mice with conditional deficiency of gp96 in macrophages and found that this protein is an important chaperone for all Toll-like receptors that have been tested.

引用

页码：141 / 143

页数：3

共 5 条

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IMMUNITY, 2007, 26 (02) :215-226

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