Heat shock protein 90 in endothelial nitric oxide synthase signaling - Following the lead(er)?

被引:45
作者
Balligand, JL [1 ]
机构
[1] Univ Catholique Louvain, Sch Med, Dept Med, Unit Pharmacol & Therapeut, B-1200 Brussels, Belgium
关键词
nitric oxide; caveolin; heat shock protein 90; endothelium;
D O I
10.1161/01.RES.0000018173.10175.FF
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
引用
收藏
页码:838 / 841
页数:4
相关论文
共 18 条
[1]   Hsp90 ensures the transition from the early Ca2+-dependent to the late phosphorylation-dependent activation of the endothelial nitric-oxide synthase in vascular endothelial growth factor-exposed endothelial cells [J].
Brouet, A ;
Sonveaux, P ;
Dessy, C ;
Balligand, JL ;
Feron, O .
JOURNAL OF BIOLOGICAL CHEMISTRY, 2001, 276 (35) :32663-32669
[2]   Hsp90 and caveolin are key targets for the proangiogenic nitric oxide-mediated effects of statins [J].
Brouet, A ;
Sonveaux, P ;
Dessy, C ;
Moniotte, S ;
Balligand, JL ;
Feron, O .
CIRCULATION RESEARCH, 2001, 89 (10) :866-873
[3]   NOSIP, a novel modulator of endothelial nitric oxide synthase activity [J].
Dedio, J ;
König, P ;
Wohlfart, P ;
Schroeder, C ;
Kummer, W ;
Müller-Esterl, W .
FASEB JOURNAL, 2001, 15 (01) :79-89
[4]   Activation of nitric oxide synthase in endothelial cells by Akt-dependent phosphorylation [J].
Dimmeler, S ;
Fleming, I ;
Fisslthaler, B ;
Hermann, C ;
Busse, R ;
Zeiher, AM .
NATURE, 1999, 399 (6736) :601-605
[5]   Loss of caveolae, vascular dysfunction, and pulmonary defects in caveolin-1 gene-disrupted mice [J].
Drab, M ;
Verkade, P ;
Elger, M ;
Kasper, M ;
Lohn, M ;
Lauterbach, B ;
Menne, J ;
Lindschau, C ;
Mende, F ;
Luft, FC ;
Schedl, A ;
Haller, H ;
Kurzchalia, TV .
SCIENCE, 2001, 293 (5539) :2449-2452
[6]  
Feron O, 2001, CIRCULATION, V103, P113
[7]   Dynamic regulation of endothelial nitric oxide synthase: Complementary roles of dual acylation and caveolin interactions [J].
Feron, O ;
Michel, JB ;
Sase, K ;
Michel, T .
BIOCHEMISTRY, 1998, 37 (01) :193-200
[8]   Phosphorylation of Thr495 regulates Ca2+/calmodulin-dependent endothelial nitric oxide synthase activity [J].
Fleming, I ;
Fisslthaler, B ;
Dimmeler, S ;
Kemp, BE ;
Busse, R .
CIRCULATION RESEARCH, 2001, 88 (11) :E68-E75
[9]   Domain mapping studies reveal that the M domain of hsp90 serves as a molecular scaffold to regulate Akt-dependent phosphorylation of endothelial nitric oxide synthase and NO release [J].
Fontana, J ;
Fulton, D ;
Chen, Y ;
Fairchild, TA ;
McCabe, TJ ;
Fujita, N ;
Tsuruo, T ;
Sessa, WC .
CIRCULATION RESEARCH, 2002, 90 (08) :866-873
[10]   Regulation of endothelium-derived nitric oxide production by the protein kinase Akt [J].
Fulton, D ;
Gratton, JP ;
McCabe, TJ ;
Fontana, J ;
Fujio, Y ;
Walsh, K ;
Franke, TF ;
Papapetropoulos, A ;
Sessa, WC .
NATURE, 1999, 399 (6736) :597-601