Na+/Ca2+ exchange inhibitors: Potential drugs to mitigate the severity of ischemic injury

被引:18
作者
Akabas, MH
机构
[1] Yeshiva Univ Albert Einstein Coll Med, Dept Physiol & Biophys, Bronx, NY 10461 USA
[2] Yeshiva Univ Albert Einstein Coll Med, Dept Neurosci, Bronx, NY 10461 USA
关键词
D O I
10.1124/mol.104.000232
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
引用
收藏
页码:8 / 10
页数:3
相关论文
共 38 条
[1]   Na+/H+ exchange inhibitors for cardioprotective therapy:: Progress, problems and prospects [J].
Avkiran, M ;
Marber, MS .
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2002, 39 (05) :747-753
[2]   Resting membrane potential regulates Na+-Ca2+ exchange-mediated Ca2+ overload during hypoxia-reoxygenation in rat ventricular myocytes [J].
Baczkó, I ;
Giles, WR ;
Light, PE .
JOURNAL OF PHYSIOLOGY-LONDON, 2003, 550 (03) :889-898
[3]   Mechanisms underlying hypoxia-induced neuronal apoptosis [J].
Banasiak, KJ ;
Xia, Y ;
Haddad, GG .
PROGRESS IN NEUROBIOLOGY, 2000, 62 (03) :215-249
[4]   Sodium calcium exchange: Its physiological implications [J].
Blaustein, MP ;
Lederer, WJ .
PHYSIOLOGICAL REVIEWS, 1999, 79 (03) :763-854
[5]   Effects of SEA0400 on mutant NCX1.1 Na+-Ca2+ exchangers with altered ionic regulation [J].
Bouchard, R ;
Omelchenko, A ;
Le, HD ;
Choptiany, P ;
Matsuda, T ;
Baba, A ;
Takahashi, K ;
Nicoll, DA ;
Philipson, KD ;
Hnatowich, M ;
Hryshko, LV .
MOLECULAR PHARMACOLOGY, 2004, 65 (03) :802-810
[6]   The vulnerable plaque and acute coronary syndromes [J].
Corti, R ;
Farkouh, ME ;
Badimon, JJ .
AMERICAN JOURNAL OF MEDICINE, 2002, 113 (08) :668-680
[7]   Co-localization of sodium channel Nav1.6 and the sodium-calcium exchanger at sites of axonal injury in the spinal cord in EAE [J].
Craner, MJ ;
Hains, BC ;
Lo, AC ;
Black, JA ;
Waxman, SG .
BRAIN, 2004, 127 :294-303
[8]   Overexpression of the cardiac Na+/Ca2+ exchanger increases susceptibility to ischemia/reperfusion injury in male, but not female, transgenic mice [J].
Cross, HR ;
Lu, LY ;
Steenbergen, C ;
Philipson, KD ;
Murphy, E .
CIRCULATION RESEARCH, 1998, 83 (12) :1215-1223
[9]   Inhibition of Na+/Ca2+ exchange by KB-R7943:: transport mode selectivity and antiarrhythmic consequences [J].
Elias, CL ;
Lukas, A ;
Shurraw, S ;
Scott, J ;
Omelchenko, A ;
Gross, GJ ;
Hnatowich, M ;
Hryshko, LV .
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY, 2001, 281 (03) :H1334-H1345
[10]   Na+/Ca2+ exchanger expression in the developing rat cortex [J].
Gibney, GT ;
Zhang, JH ;
Douglas, RM ;
Haddad, GG ;
Xia, Y .
NEUROSCIENCE, 2002, 112 (01) :65-73