Physiologic studies in the human brain in movement disorders

被引：13

作者：

Lozano, AM

Carella, F

机构：

[1] Toronto Western Hosp, Res Inst, Div Neurosurg, Dept Surg, Toronto, ON M5T 2S8, Canada

[2] Univ Toronto, Dept Physiol, Toronto, ON M5T 2S8, Canada

来源：

PARKINSONISM & RELATED DISORDERS | 2002年 / 8卷 / 06期

关键词：

basal ganglia; neurophysiology; microelectrode recording; Parkinson's disease;

D O I：

10.1016/S1353-8020(02)00027-5

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Physiologic studies are useful in identifying brain targets during functional neurosurgical procedures for the treatment of Parkinson's disease and other movement disorders. These studies also open a window into the function and dysfunction in the basal ganglia. Recording of the activity of single neurons in the motor thalamus, the globus pallidus or the subthalamic nucleus with microelectrodes is providing important insights into the pathophysiology of parkinsonism and the mechanism of action of medical therapy and surgical interventions. (C) 2002 Published by Elsevier Science Ltd.

引用

页码：455 / 458

页数：4

共 28 条

[1] Neurophysiological effects of stimulation through electrodes in the human subthalamic nucleus [J].