Inhibitory effects on Epstein-Barr virus activation of anthraquinones: Correlation with redox potentials

被引：17

作者：

Koyama, J

Tagahara, K

Osakai, T

Tsujino, Y

Tsurumi, S

Nishino, H

Tokuda, H

机构：

[1] YAMAHATSU SANGYO KAISHA LTD,DEPT RES & DEV,NISHINARI,OSAKA 557,JAPAN

[2] KOBE UNIV,GRAD SCH SCI & TECHNOL,NADA KU,KOBE,HYOGO 657,JAPAN

[3] KOBE UNIV,FAC SCI,DEPT CHEM,NADA KU,KOBE,HYOGO 657,JAPAN

[4] KYOTO PREFECTURAL UNIV MED,DEPT BIOCHEM,KYOTO 602,JAPAN

来源：

CANCER LETTERS | 1997年 / 115卷 / 02期

关键词：

anti-tumor promoting effect; anthraquinones; Epstein-Barr virus activation; standard redox potential; cyclic voltammetry; atomic charge;

D O I：

10.1016/S0304-3835(97)04734-4

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

The redox potentials have been determined for nine anthraquinones in phosphate buffer at pH 7.2 by means of cyclic voltammetry. A definite correlation has been found between the redox potentials and the inhibitory effects of the anthraquinones on the EBV-EA activation. It has further been shown that the correlation can be made better by introducing an electronic property, i.e. the atomic charge at O-12 as an additional parameter. (C) 1997 Elsevier Science Ireland Ltd.

引用

页码：179 / 183

页数：5

共 13 条

[1] STUDIES ON INHIBITORS OF SKIN-TUMOR PROMOTION - INHIBITORY EFFECTS OF TRITERPENES FROM COCHLOSPERMUM-TINCTORIUM ON EPSTEIN-BARR VIRUS-ACTIVATION [J].